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Lastly, our findings suggest that the CRF-R1 receptor and the beta-2 AR may serve as viable medicinal targets for the management of relapse, particularly in individuals whose drug use is stress driven.
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Drug-associated environmental cues critically contribute to relapse to drug-seeking behavior in abstinent addicts. I will, however, refer you to an Article written by S.
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These rats exhibited less preference for saccharin, lower weight gain, and disruption of estrous cycles. This pattern of changes suggests a decrease in cocaine reinforcement and attenuation of the incentive motivational effects of cocaine-priming injections and cocaine-associated cues during protracted withdrawal.
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